Retarding breast tumor growth with nanoparticle-facilitated intravenous delivery of BRCA1 and BRCA2 tumor suppressor genes

Gene augmentation therapy entails replacement of the abnormal tumor suppressor genes in cancer cells. In this study, we performed gene augmentation for BRCA1/2 tumor suppressors in order to retard tumor development in breast cancer mouse model. We formulated inorganic carbonate apatite (CA) nanopart...

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Detalles Bibliográficos
Autores principales: Ibnat, Nabilah, Chowdhury, Ezharul Hoque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834397/
https://www.ncbi.nlm.nih.gov/pubmed/36631481
http://dx.doi.org/10.1038/s41598-022-25511-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834397/
https://www.ncbi.nlm.nih.gov/pubmed/36631481
http://dx.doi.org/10.1038/s41598-022-25511-9

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