The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators

The heptad repeats of the C-terminal domain (CTD) of RNA polymerase II (Pol II) are extensively modified throughout the transcription cycle. The CTD coordinates RNA synthesis and processing by recruiting transcription regulators as well as RNA capping, splicing and 3’end processing factors. The SPOC...

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Detalles Bibliográficos
Autores principales: Appel, Lisa-Marie, Franke, Vedran, Benedum, Johannes, Grishkovskaya, Irina, Strobl, Xué, Polyansky, Anton, Ammann, Gregor, Platzer, Sebastian, Neudolt, Andrea, Wunder, Anna, Walch, Lena, Kaiser, Stefanie, Zagrovic, Bojan, Djinovic-Carugo, Kristina, Akalin, Altuna, Slade, Dea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834408/
https://www.ncbi.nlm.nih.gov/pubmed/36631525
http://dx.doi.org/10.1038/s41467-023-35853-1

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