Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report

High‐grade fetal lung adenocarcinoma (H‐FLAC) is a rare tumor, with little known of its response to chemotherapy with or without an immune checkpoint inhibitor or of its molecular profile. We report the first case of a 56‐year‐old man with stage IV H‐FLAC who was successfully treated with carboplati...

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Autores principales: Fujimoto, Kana, Watanabe, Satomi, Yasuda, Yuto, Date, Emi, Kawabata, Yasuhiro, Kanemura, Hiroaki, Takahama, Takayuki, Yonesaka, Kimio, Iizuka, Norishige, Takahashi, Ken‐ichi, Kawakami, Osamu, Ozaki, Tomohiro, Nakagawa, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834689/
https://www.ncbi.nlm.nih.gov/pubmed/36495048
http://dx.doi.org/10.1111/1759-7714.14768
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author Fujimoto, Kana
Watanabe, Satomi
Yasuda, Yuto
Date, Emi
Kawabata, Yasuhiro
Kanemura, Hiroaki
Takahama, Takayuki
Yonesaka, Kimio
Iizuka, Norishige
Takahashi, Ken‐ichi
Kawakami, Osamu
Ozaki, Tomohiro
Nakagawa, Kazuhiko
author_facet Fujimoto, Kana
Watanabe, Satomi
Yasuda, Yuto
Date, Emi
Kawabata, Yasuhiro
Kanemura, Hiroaki
Takahama, Takayuki
Yonesaka, Kimio
Iizuka, Norishige
Takahashi, Ken‐ichi
Kawakami, Osamu
Ozaki, Tomohiro
Nakagawa, Kazuhiko
author_sort Fujimoto, Kana
collection PubMed
description High‐grade fetal lung adenocarcinoma (H‐FLAC) is a rare tumor, with little known of its response to chemotherapy with or without an immune checkpoint inhibitor or of its molecular profile. We report the first case of a 56‐year‐old man with stage IV H‐FLAC who was successfully treated with carboplatin plus nab‐paclitaxel in combination with atezolizumab. In addition, the tumor was found to be positive for amplification of the human epidermal growth factor receptor 2 gene.
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spelling pubmed-98346892023-01-17 Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report Fujimoto, Kana Watanabe, Satomi Yasuda, Yuto Date, Emi Kawabata, Yasuhiro Kanemura, Hiroaki Takahama, Takayuki Yonesaka, Kimio Iizuka, Norishige Takahashi, Ken‐ichi Kawakami, Osamu Ozaki, Tomohiro Nakagawa, Kazuhiko Thorac Cancer Case Reports High‐grade fetal lung adenocarcinoma (H‐FLAC) is a rare tumor, with little known of its response to chemotherapy with or without an immune checkpoint inhibitor or of its molecular profile. We report the first case of a 56‐year‐old man with stage IV H‐FLAC who was successfully treated with carboplatin plus nab‐paclitaxel in combination with atezolizumab. In addition, the tumor was found to be positive for amplification of the human epidermal growth factor receptor 2 gene. John Wiley & Sons Australia, Ltd 2022-12-09 /pmc/articles/PMC9834689/ /pubmed/36495048 http://dx.doi.org/10.1111/1759-7714.14768 Text en © 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Fujimoto, Kana
Watanabe, Satomi
Yasuda, Yuto
Date, Emi
Kawabata, Yasuhiro
Kanemura, Hiroaki
Takahama, Takayuki
Yonesaka, Kimio
Iizuka, Norishige
Takahashi, Ken‐ichi
Kawakami, Osamu
Ozaki, Tomohiro
Nakagawa, Kazuhiko
Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
title Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
title_full Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
title_fullStr Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
title_full_unstemmed Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
title_short Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
title_sort successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834689/
https://www.ncbi.nlm.nih.gov/pubmed/36495048
http://dx.doi.org/10.1111/1759-7714.14768
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