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Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report

Cryptococcosis is an invasive fungal infection that can occur in cancer patients. A case of pulmonary cryptococcosis in a patient treated with erlotinib + ramucirumab for epidermal growth factor receptor (EGFR) L858R point mutation‐positive non‐small cell lung cancer is presented. During chemotherap...

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Detalles Bibliográficos
Autores principales: Kobe, Hiroshi, Yokoe, Shinya, Ishida, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834699/
https://www.ncbi.nlm.nih.gov/pubmed/36450693
http://dx.doi.org/10.1111/1759-7714.14753
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author Kobe, Hiroshi
Yokoe, Shinya
Ishida, Tadashi
author_facet Kobe, Hiroshi
Yokoe, Shinya
Ishida, Tadashi
author_sort Kobe, Hiroshi
collection PubMed
description Cryptococcosis is an invasive fungal infection that can occur in cancer patients. A case of pulmonary cryptococcosis in a patient treated with erlotinib + ramucirumab for epidermal growth factor receptor (EGFR) L858R point mutation‐positive non‐small cell lung cancer is presented. During chemotherapy, a new pulmonary nodule was found and considered progressive disease. Examination of the biopsy specimen taken to identify EGFR T790M mutation incidentally led to the diagnosis of pulmonary cryptococcosis. Three months after taking fluconazole, chest computed tomography showed that the pulmonary nodule had shrunk. New pulmonary nodules during lung cancer treatment require careful attention, not only because of disease progression, but also because of the possibility of infection in an immunocompromised host.
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spelling pubmed-98346992023-01-17 Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report Kobe, Hiroshi Yokoe, Shinya Ishida, Tadashi Thorac Cancer Case Reports Cryptococcosis is an invasive fungal infection that can occur in cancer patients. A case of pulmonary cryptococcosis in a patient treated with erlotinib + ramucirumab for epidermal growth factor receptor (EGFR) L858R point mutation‐positive non‐small cell lung cancer is presented. During chemotherapy, a new pulmonary nodule was found and considered progressive disease. Examination of the biopsy specimen taken to identify EGFR T790M mutation incidentally led to the diagnosis of pulmonary cryptococcosis. Three months after taking fluconazole, chest computed tomography showed that the pulmonary nodule had shrunk. New pulmonary nodules during lung cancer treatment require careful attention, not only because of disease progression, but also because of the possibility of infection in an immunocompromised host. John Wiley & Sons Australia, Ltd 2022-11-30 /pmc/articles/PMC9834699/ /pubmed/36450693 http://dx.doi.org/10.1111/1759-7714.14753 Text en © 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Kobe, Hiroshi
Yokoe, Shinya
Ishida, Tadashi
Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report
title Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report
title_full Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report
title_fullStr Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report
title_full_unstemmed Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report
title_short Incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor T790M mutation: A case report
title_sort incidental diagnosis of pulmonary cryptococcosis by rebiopsy for epidermal growth factor receptor t790m mutation: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834699/
https://www.ncbi.nlm.nih.gov/pubmed/36450693
http://dx.doi.org/10.1111/1759-7714.14753
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