POEMS syndrome presents with a distended abdomen: A case report

POEMS syndrome is a rare, serious, multisystem disorder and its diagnosis is frequently missed due to its varied clinical presentation. We report here, a 69-year-old woman with initial complaints of distended abdomen, who was misdiagnosed with tuberculosis but failed anti-tuberculosis treatment. Fur...

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Detalles Bibliográficos
Autores principales: Wang, Wenshu, Yang, Guibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834793/
https://www.ncbi.nlm.nih.gov/pubmed/36624979
http://dx.doi.org/10.1177/03000605221148410
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author Wang, Wenshu
Yang, Guibin
author_facet Wang, Wenshu
Yang, Guibin
author_sort Wang, Wenshu
collection PubMed
description POEMS syndrome is a rare, serious, multisystem disorder and its diagnosis is frequently missed due to its varied clinical presentation. We report here, a 69-year-old woman with initial complaints of distended abdomen, who was misdiagnosed with tuberculosis but failed anti-tuberculosis treatment. Further examinations showed peripheral neuropathy, monoclonal plasma cell disease, sclerotic bone lesions, an elevated serum vascular endothelial growth factor (VEGF) concentration, lymph node hyperplasia, endocrine abnormalities, and skin hyperpigmentation. A diagnosis of POEMS syndrome was made and the patient responded to lenalidomide-based chemotherapy.
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spelling pubmed-98347932023-01-13 POEMS syndrome presents with a distended abdomen: A case report Wang, Wenshu Yang, Guibin J Int Med Res Case Reports POEMS syndrome is a rare, serious, multisystem disorder and its diagnosis is frequently missed due to its varied clinical presentation. We report here, a 69-year-old woman with initial complaints of distended abdomen, who was misdiagnosed with tuberculosis but failed anti-tuberculosis treatment. Further examinations showed peripheral neuropathy, monoclonal plasma cell disease, sclerotic bone lesions, an elevated serum vascular endothelial growth factor (VEGF) concentration, lymph node hyperplasia, endocrine abnormalities, and skin hyperpigmentation. A diagnosis of POEMS syndrome was made and the patient responded to lenalidomide-based chemotherapy. SAGE Publications 2023-01-09 /pmc/articles/PMC9834793/ /pubmed/36624979 http://dx.doi.org/10.1177/03000605221148410 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Wang, Wenshu
Yang, Guibin
POEMS syndrome presents with a distended abdomen: A case report
title POEMS syndrome presents with a distended abdomen: A case report
title_full POEMS syndrome presents with a distended abdomen: A case report
title_fullStr POEMS syndrome presents with a distended abdomen: A case report
title_full_unstemmed POEMS syndrome presents with a distended abdomen: A case report
title_short POEMS syndrome presents with a distended abdomen: A case report
title_sort poems syndrome presents with a distended abdomen: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834793/
https://www.ncbi.nlm.nih.gov/pubmed/36624979
http://dx.doi.org/10.1177/03000605221148410
work_keys_str_mv AT wangwenshu poemssyndromepresentswithadistendedabdomenacasereport
AT yangguibin poemssyndromepresentswithadistendedabdomenacasereport

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