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Optimization of protein removal process of Lonicera japonica polysaccharide and its immunomodulatory mechanism in cyclophosphamide‐induced mice by metabolomics and network pharmacology
In this study, TCA–n‐butanol was chosen as the best deproteinization method for Lonicera japonica polysaccharide (LJP) by comparing the polysaccharide retention rate and the protein clearance rate of five different methods. The response surface methodology (RSM) based on the Box–Behnken design (BBD)...
Autores principales: | Ding, Jie, Du, Haitao, Tan, Haining, Li, Jing, Wang, Lingna, Li, Li, Zhang, Yongqing, Liu, Yuhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834838/ https://www.ncbi.nlm.nih.gov/pubmed/36655085 http://dx.doi.org/10.1002/fsn3.3067 |
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