Caspase-8 contributes to an immuno-hot microenvironment by promoting phagocytosis via an ecto-calreticulin-dependent mechanism

BACKGROUND: Caspase-8 (Casp8) acts as an initiator in cell apoptosis signaling. However, the role of Casp8 in tuning the tumor immune microenvironment remains controversial due to the complicated crosstalk between immune-tolerogenic apoptotic cell death and immunogenic cell death cascades. METHODS:...

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Detalles Bibliográficos
Autores principales: Gong, Zhihua, Jia, Qingzhu, Guo, Jinming, Li, Chongyi, Xu, Shouxia, Jin, Zheng, Chu, Han, Wan, Yisong Y., Zhu, Bo, Zhou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835222/
https://www.ncbi.nlm.nih.gov/pubmed/36635765
http://dx.doi.org/10.1186/s40164-022-00371-1

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