Current practice and recommendations for advancing how human variability and susceptibility are considered in chemical risk assessment

A key element of risk assessment is accounting for the full range of variability in response to environmental exposures. Default dose-response methods typically assume a 10-fold difference in response to chemical exposures between average (healthy) and susceptible humans, despite evidence of wider v...

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Detalles Bibliográficos
Autores principales: Varshavsky, Julia R., Rayasam, Swati D. G., Sass, Jennifer B., Axelrad, Daniel A., Cranor, Carl F., Hattis, Dale, Hauser, Russ, Koman, Patricia D., Marquez, Emily C., Morello-Frosch, Rachel, Oksas, Catherine, Patton, Sharyle, Robinson, Joshua F., Sathyanarayana, Sheela, Shepard, Peggy M., Woodruff, Tracey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835253/
https://www.ncbi.nlm.nih.gov/pubmed/36635753
http://dx.doi.org/10.1186/s12940-022-00940-1

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