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AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway

BACKGROUND: The actin filament-associated protein (AFAP) family genes include AFAP1/AFAP-110, AFAP1L1 and AFAP1L2/XB130. Increasing evidence indicates these three AFAP family members participate in tumor progression, but their clinical significance and molecular mechanisms in gastric cancer (GC) rem...

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Detalles Bibliográficos
Autores principales: Sun, Bo, Ding, Bai, Chen, Yu, Peng, Chuang, Chen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835296/
https://www.ncbi.nlm.nih.gov/pubmed/36631800
http://dx.doi.org/10.1186/s12967-023-03871-8