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A machine learning framework develops a DNA replication stress model for predicting clinical outcomes and therapeutic vulnerability in primary prostate cancer
Recent studies have identified DNA replication stress as an important feature of advanced prostate cancer (PCa). The identification of biomarkers for DNA replication stress could therefore facilitate risk stratification and help inform treatment options for PCa. Here, we designed a robust machine le...
Autores principales: | Huang, Rong-Hua, Hong, Ying-Kai, Du, Heng, Ke, Wei-Qi, Lin, Bing-Biao, Li, Ya-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835390/ https://www.ncbi.nlm.nih.gov/pubmed/36635710 http://dx.doi.org/10.1186/s12967-023-03872-7 |
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