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Exosomal miR‐532‐5p induced by long‐term exercise rescues blood–brain barrier function in 5XFAD mice via downregulation of EPHA4
The breakdown of the blood–brain barrier, which develops early in Alzheimer's disease (AD), contributes to cognitive impairment. Exercise not only reduces the risk factors for AD but also confers direct protection against cognitive decline. However, the exact molecular mechanisms remain elusive...
Autores principales: | Liang, Xiaoyan, Fa, Wenxin, Wang, Nan, Peng, Yuanming, Liu, Cuicui, Zhu, Min, Tian, Na, Wang, Yongxiang, Han, Xiaolei, Qiu, Chengxuan, Hou, Tingting, Du, Yifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835579/ https://www.ncbi.nlm.nih.gov/pubmed/36494892 http://dx.doi.org/10.1111/acel.13748 |
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