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Exosomal miR‐532‐5p induced by long‐term exercise rescues blood–brain barrier function in 5XFAD mice via downregulation of EPHA4

The breakdown of the blood–brain barrier, which develops early in Alzheimer's disease (AD), contributes to cognitive impairment. Exercise not only reduces the risk factors for AD but also confers direct protection against cognitive decline. However, the exact molecular mechanisms remain elusive...

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Detalles Bibliográficos
Autores principales: Liang, Xiaoyan, Fa, Wenxin, Wang, Nan, Peng, Yuanming, Liu, Cuicui, Zhu, Min, Tian, Na, Wang, Yongxiang, Han, Xiaolei, Qiu, Chengxuan, Hou, Tingting, Du, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835579/
https://www.ncbi.nlm.nih.gov/pubmed/36494892
http://dx.doi.org/10.1111/acel.13748

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