Allosteric inhibition of Staphylococcus aureus MenD by 1,4-dihydroxy naphthoic acid: a feedback inhibition mechanism of the menaquinone biosynthesis pathway

Menaquinones (MKs) are electron carriers in bacterial respiratory chains. In Staphylococcus aureus (Sau), MKs are essential for aerobic and anaerobic respiration. As MKs are redox-active, their biosynthesis likely requires tight regulation to prevent disruption of cellular redox balance. We recently...

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Detalles Bibliográficos
Autores principales: Stanborough, Tamsyn, Ho, Ngoc Anh Thu, Bulloch, Esther M. M., Bashiri, Ghader, Dawes, Stephanie S., Akazong, Etheline W., Titterington, James, Allison, Timothy M., Jiao, Wanting, Johnston, Jodie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835592/
https://www.ncbi.nlm.nih.gov/pubmed/36633276
http://dx.doi.org/10.1098/rstb.2022.0035

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