Success probability of high-affinity DNA aptamer generation by genetic alphabet expansion

Nucleic acid aptamers as antibody alternatives bind specifically to target molecules. These aptamers are generated by isolating candidates from libraries with random sequence fragments, through an evolutionary engineering system. We recently reported a high-affinity DNA aptamer generation method tha...

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Detalles Bibliográficos
Autores principales: Kimoto, Michiko, Tan, Hui Pen, Tan, Yaw Sing, Mislan, Nur Afiqah Binte Mohd, Hirao, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835594/
https://www.ncbi.nlm.nih.gov/pubmed/36633272
http://dx.doi.org/10.1098/rstb.2022.0031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835594/
https://www.ncbi.nlm.nih.gov/pubmed/36633272
http://dx.doi.org/10.1098/rstb.2022.0031

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