(18)F-FDG PET/CT Findings of Leptomeningeal Metastasis in Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NC) is an epithelial tumor with distinctive prevalence in East and Southeast Asia. Most patients with NC only experience regional metastasis. In cases of distant metastasis, prognosis is grim. Leptomeningeal spread of the disease is a rare occurrence, which is sparsely desc...

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Detalles Bibliográficos
Autores principales: Montanarella, Matthew, Boldig, Kimberly, Natter, Patrick, Ozdemir, Savas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835668/
https://www.ncbi.nlm.nih.gov/pubmed/36562736
http://dx.doi.org/10.1097/RLU.0000000000004499
Descripción
Sumario:Nasopharyngeal carcinoma (NC) is an epithelial tumor with distinctive prevalence in East and Southeast Asia. Most patients with NC only experience regional metastasis. In cases of distant metastasis, prognosis is grim. Leptomeningeal spread of the disease is a rare occurrence, which is sparsely described in the literature. We present a case of a 33-year-old man with a history of high-grade NC with leptomeningeal metastasis. Initial MRI lumbar spine demonstrated subtle findings consistent with leptomeningeal disease. These findings are easily discernible on (18)F-FDG PET/CT.

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