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FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes

PURPOSE: To present FIAT, a novel optical instrument and analysis package that is designed to elicit and optically record accommodation in human eyes. METHODS: FIAT employs a Shack-Hartmann wavefront sensor and a retro-illumination pupil camera that records from a single eye at video rates. It is ef...

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Autores principales: Roorda, Austin, Tiruveedhula, Pavan, Naseri, Ayman, Rhee, Paul, Clarke, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836010/
https://www.ncbi.nlm.nih.gov/pubmed/36607622
http://dx.doi.org/10.1167/tvst.12.1.9
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author Roorda, Austin
Tiruveedhula, Pavan
Naseri, Ayman
Rhee, Paul
Clarke, Matt
author_facet Roorda, Austin
Tiruveedhula, Pavan
Naseri, Ayman
Rhee, Paul
Clarke, Matt
author_sort Roorda, Austin
collection PubMed
description PURPOSE: To present FIAT, a novel optical instrument and analysis package that is designed to elicit and optically record accommodation in human eyes. METHODS: FIAT employs a Shack-Hartmann wavefront sensor and a retro-illumination pupil camera that records from a single eye at video rates. It is effective at eliciting accommodation by offering the subject a full-field binocular view of an alternating distant target and a near-eye display. FIAT analysis software computes wave aberrations for each video frame over full- or subpupil sizes and computes accommodative dynamics and accommodative range. RESULTS: The system is validated by showing accurate refraction measurements in model eyes and human eyes with trial lenses. Robust accommodative responses are shown for young eyes, and a lack of accommodative response is shown for a known presbyopes. Accommodative stimulus–response curves from five phakic subjects over a range of ages show expected results. Results from two individuals with monofocal intraocular lenses are shown. CONCLUSIONS: FIAT is an effective instrument for making accurate, objective measures of accommodation in phakic and pseudophakic eyes. TRANSLATIONAL RELEVANCE: We present a device that can play an important role in the development and testing of accommodating intraocular lenses.
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spelling pubmed-98360102023-01-13 FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes Roorda, Austin Tiruveedhula, Pavan Naseri, Ayman Rhee, Paul Clarke, Matt Transl Vis Sci Technol Refractive Intervention PURPOSE: To present FIAT, a novel optical instrument and analysis package that is designed to elicit and optically record accommodation in human eyes. METHODS: FIAT employs a Shack-Hartmann wavefront sensor and a retro-illumination pupil camera that records from a single eye at video rates. It is effective at eliciting accommodation by offering the subject a full-field binocular view of an alternating distant target and a near-eye display. FIAT analysis software computes wave aberrations for each video frame over full- or subpupil sizes and computes accommodative dynamics and accommodative range. RESULTS: The system is validated by showing accurate refraction measurements in model eyes and human eyes with trial lenses. Robust accommodative responses are shown for young eyes, and a lack of accommodative response is shown for a known presbyopes. Accommodative stimulus–response curves from five phakic subjects over a range of ages show expected results. Results from two individuals with monofocal intraocular lenses are shown. CONCLUSIONS: FIAT is an effective instrument for making accurate, objective measures of accommodation in phakic and pseudophakic eyes. TRANSLATIONAL RELEVANCE: We present a device that can play an important role in the development and testing of accommodating intraocular lenses. The Association for Research in Vision and Ophthalmology 2023-01-06 /pmc/articles/PMC9836010/ /pubmed/36607622 http://dx.doi.org/10.1167/tvst.12.1.9 Text en Copyright 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Refractive Intervention
Roorda, Austin
Tiruveedhula, Pavan
Naseri, Ayman
Rhee, Paul
Clarke, Matt
FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes
title FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes
title_full FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes
title_fullStr FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes
title_full_unstemmed FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes
title_short FIAT: A Device for Objective, Optical Measures of Accommodation in Phakic and Pseudophakic Eyes
title_sort fiat: a device for objective, optical measures of accommodation in phakic and pseudophakic eyes
topic Refractive Intervention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836010/
https://www.ncbi.nlm.nih.gov/pubmed/36607622
http://dx.doi.org/10.1167/tvst.12.1.9
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