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The Comparison of QTc Dispersion Between Renal Transplant Recipients and Healthy Individuals

Introduction Cardiovascular diseases are the most common cause of death in patients with end-stage renal failure. The increase in QTc interval time and QT dispersion increases the risk of cardiac arrhythmia and mortality. In our study, QT and QTc dispersions (QTcd) of patients who underwent renal tr...

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Detalles Bibliográficos
Autores principales: Durak, Musa Ilker, Algul Durak, Beyza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836013/
https://www.ncbi.nlm.nih.gov/pubmed/36644076
http://dx.doi.org/10.7759/cureus.32458
Descripción
Sumario:Introduction Cardiovascular diseases are the most common cause of death in patients with end-stage renal failure. The increase in QTc interval time and QT dispersion increases the risk of cardiac arrhythmia and mortality. In our study, QT and QTc dispersions (QTcd) of patients who underwent renal transplantation were compared with normal healthy individuals. Methods Electrocardiograms (ECGs) of 80 renal transplant recipients and 70 healthy individuals were taken. QTc dispersion was calculated by using the longest and the shortest QT interval and QT dispersion and Bazett's formula. Results When the groups were compared, similar QT dispersion and QTc dispersion were observed (control group and renal transplant recipient patients: 35 ± 17 ms and 36 ± 16 ms and 52 ± 18 ms and 54 ± 22 ms, respectively). Conclusion No statistical difference was observed between QT and QTc dispersions of renal transplant patients compared to healthy individuals. This result shows that the increase in QT dispersion and pathophysiological mechanisms observed frequently in uremic patients can be reversed by renal transplantation.