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RNA polymerase II transcription attenuation at the yeast DNA repair gene DEF1 is biologically significant and dependent on the Hrp1 RNA-recognition motif

Premature transcription termination (i.e. attenuation) is a potent gene regulatory mechanism that represses mRNA synthesis. Attenuation of RNA polymerase II is more prevalent than once appreciated, targeting 10–15% of mRNA genes in yeast through higher eukaryotes, but its significance and mechanism...

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Detalles Bibliográficos
Autores principales:	Amodeo, Maria E, Mitchell, Shane P C, Pavan, Vincent, Kuehner, Jason N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836349/ https://www.ncbi.nlm.nih.gov/pubmed/36315099 http://dx.doi.org/10.1093/g3journal/jkac292

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