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TREM2‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology

The existence of individuals who remain cognitively intact despite presenting histopathological signs of Alzheimer's disease (AD), here referred to as “Nondemented with AD neuropathology” (NDAN), suggests that some mechanisms are triggered to resist cognitive impairment. Exposed phosphatidylser...

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Detalles Bibliográficos
Autores principales: Fracassi, Anna, Marcatti, Michela, Tumurbaatar, Batbayar, Woltjer, Randall, Moreno, Sandra, Taglialatela, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836373/
https://www.ncbi.nlm.nih.gov/pubmed/35816404
http://dx.doi.org/10.1111/bpa.13108