Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels

Overexpression of the dihydrolipoamide S-succinyltransferase (DLST) is associated with poor outcome in neuroblastoma patients and triple-negative breast cancer (TNBC) and specifically with the oxidative phosphorylation (OXPHOS) pathway. Inhibitors of OXPHOS were previously suggested as a potential t...

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Detalles Bibliográficos
Autores principales: Kuhn, Christina, Boeschen, Myriam, Philip, Manuel, Schöneberg, Torsten, Thor, Doreen, Horn, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836382/
https://www.ncbi.nlm.nih.gov/pubmed/36634214
http://dx.doi.org/10.18632/oncotarget.28342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836382/
https://www.ncbi.nlm.nih.gov/pubmed/36634214
http://dx.doi.org/10.18632/oncotarget.28342

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