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Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels
Overexpression of the dihydrolipoamide S-succinyltransferase (DLST) is associated with poor outcome in neuroblastoma patients and triple-negative breast cancer (TNBC) and specifically with the oxidative phosphorylation (OXPHOS) pathway. Inhibitors of OXPHOS were previously suggested as a potential t...
Autores principales: | Kuhn, Christina, Boeschen, Myriam, Philip, Manuel, Schöneberg, Torsten, Thor, Doreen, Horn, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836382/ https://www.ncbi.nlm.nih.gov/pubmed/36634214 http://dx.doi.org/10.18632/oncotarget.28342 |
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