Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001

Overexpression of CD74, a type II transmembrane glycoprotein involved in MHC class II antigen presentation, has been reported in many B-cell non-Hodgkin lymphomas (NHLs) and in multiple myeloma (MM). STRO-001 is a site-specific, predominantly single-species antibody-drug conjugate (ADC) that targets...

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Detalles Bibliográficos
Autores principales: Li, Xiaofan, Abrahams, Cristina, Yu, Abigail, Embry, Millicent, Henningsen, Robert, DeAlmeida, Venita, Matheny, Shannon, Kline, Toni, Yam, Alice, Stafford, Ryan, Hallam, Trevor, Lupher, Mark, Molina, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836384/
https://www.ncbi.nlm.nih.gov/pubmed/36634212
http://dx.doi.org/10.18632/oncotarget.28341

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