Marmesin and Marmelosin Interact with the Heparan Sulfatase-2 Active Site: Potential Mechanism for Phytochemicals from Bael Fruit Extract as Antitumor Therapeutics

Human heparan sulfatase-2 (HSULF-2) is an oncoprotein overexpressed in the surface of all types of tumor cells and its activity plays a critical role in cancer survival and progression. Our previous studies have shown that bael fruit extract, containing marmesin and marmelosin, inhibits the HSULF-2...

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Detalles Bibliográficos
Autores principales: Hemakumar, C., Ravindranath, B. S., Ravishankar, G. A., Ramirez, D. C., Kiran, S. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836799/
https://www.ncbi.nlm.nih.gov/pubmed/36644581
http://dx.doi.org/10.1155/2023/9982194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836799/
https://www.ncbi.nlm.nih.gov/pubmed/36644581
http://dx.doi.org/10.1155/2023/9982194

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