CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype

The heterogeneity of cancer-associated fibroblasts (CAFs) might be ascribed to differences in origin. CD10 and GPR77 have been reported to identify a chemoresistance-inducing CAF subset in breast cancer. However, the precise mechanism for the formation of the CD10(+)GPR77(+) CAFs remains unknown. In...

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Detalles Bibliográficos
Autores principales: Zeng, Wenfeng, Xiong, Lixiong, Wu, Wei, Li, Shunrong, Liu, Jiang, Yang, Linbing, Lao, Liyan, Huang, Penghan, Zhang, Mengmeng, Chen, Huiping, Miao, Nanyan, Lin, Zhirong, Liu, Zifei, Yang, Xinyu, Wang, Jiayi, Wang, Pei, Song, Erwei, Yao, Yandan, Nie, Yan, Chen, Jianing, Huang, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836934/
https://www.ncbi.nlm.nih.gov/pubmed/36418470
http://dx.doi.org/10.1038/s41388-022-02540-2

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