Characterization of BNT162b2 mRNA to Evaluate Risk of Off-Target Antigen Translation

mRNA vaccines have been established as a safe and effective modality, thanks in large part to the expedited development and approval of COVID-19 vaccines. In addition to the active, full-length mRNA transcript, mRNA fragment species can be present as a byproduct of the cell-free transcription manufa...

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Detalles Bibliográficos
Autores principales: Patel, Himakshi K., Zhang, Kun, Utegg, Rachael, Stephens, Elaine, Salem, Shauna, Welch, Heidi, Grobe, Svenja, Schlereth, Julia, Kuhn, Andreas N., Ryczek, Jeff, Cirelli, David J., Lerch, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. on behalf of American Pharmacists Association. 2023
Materias:
Pharmaceutical Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9836996/
https://www.ncbi.nlm.nih.gov/pubmed/36642376
http://dx.doi.org/10.1016/j.xphs.2023.01.007

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