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In silico and in vitro studies confirm Ondansetron as a novel acetylcholinesterase and butyrylcholinesterase inhibitor

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is growing rapidly among the elderly population around the world. Studies show that a lack of acetylcholine and butyrylcholine due to the overexpression of enzymes Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE) m...

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Detalles Bibliográficos
Autores principales: Gholami, Asma, Minai-Tehrani, Dariush, Eriksson, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837033/
https://www.ncbi.nlm.nih.gov/pubmed/36635365
http://dx.doi.org/10.1038/s41598-022-27149-z

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