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CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
Cancer-associated fibroblasts (CAFs) are abundantly present in the microenvironment of virtually all tumors and strongly impact tumor progression. Despite increasing insight into their function and heterogeneity, little is known regarding the origin of CAFs. Understanding the origin of CAF heterogen...
Autores principales: | Houthuijzen, Julia M., de Bruijn, Roebi, van der Burg, Eline, Drenth, Anne Paulien, Wientjens, Ellen, Filipovic, Tamara, Bullock, Esme, Brambillasca, Chiara S., Pulver, Emilia M., Nieuwland, Marja, de Rink, Iris, van Diepen, Frank, Klarenbeek, Sjoerd, Kerkhoven, Ron, Brunton, Valerie G., Scheele, Colinda L.G.J., Boelens, Mirjam C., Jonkers, Jos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837080/ https://www.ncbi.nlm.nih.gov/pubmed/36635273 http://dx.doi.org/10.1038/s41467-023-35793-w |
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