Cargando…

Combined multiomics analysis reveals the mechanism of CENPF overexpression-mediated immune dysfunction in diffuse large B-cell lymphoma in vitro

Diffuse large B-cell lymphoma (DLBCL) is one of the most common aggressive B-cell lymphomas with significant heterogeneity. More than half of patients are cured, but 40%–45% still face relapse or develop drug resistance, and the mechanism is not yet known. In this study, Centrimeric protein F (CENPF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Dan, Wang, Jia, Hu, Mingqiu, Li, Feng, Yang, Feifei, Zhao, Youcai, Xu, Yanli, Zhang, Xuezhong, Tang, Lijun, Zhang, Xiuqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837108/ https://www.ncbi.nlm.nih.gov/pubmed/36644760 http://dx.doi.org/10.3389/fgene.2022.1072689

Ejemplares similares

Overexpression of CENPF is associated with progression and poor prognosis of lung adenocarcinoma
por: Li, Mei-Xiang, et al.
Publicado: (2021)

The iron chelator deferoxamine decreases myeloma cell survival
por: Yang, Feifei, et al.
Publicado: (2021)

Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer
por: Sun, Jingbo, et al.
Publicado: (2019)

Upregulation of CENPF is linked to aggressive features of osteosarcoma
por: Zou, Ping-An, et al.
Publicado: (2021)

[Retracted] Upregulation of CENPF is linked to aggressive features of osteosarcoma
por: Zou, Ping-An, et al.
Publicado: (2023)

An Autophagy-Related Gene Signature can Better Predict Prognosis and Resistance in Diffuse Large B-Cell Lymphoma
por: Zhou, Xuan, et al.
Publicado: (2022)

Systematic Analysis of Competing Endogenous RNA Networks in Diffuse Large B-Cell Lymphoma and Hodgkin’s Lymphoma
por: Kang, Juanjuan, et al.
Publicado: (2020)

Identification of microtubule-associated biomarkers in diffuse large B-cell lymphoma and prognosis prediction
por: Wu, Wenqi, et al.
Publicado: (2023)

CENPF promotes the proliferation of renal cell carcinoma in vitro
por: Zhang, Ji, et al.
Publicado: (2023)

Diffuse large B-cell lymphoma with pulmonary and cerebral involvement: A case report
por: Zeng, Jing, et al.
Publicado: (2018)

Single-Cell RNA-Seq and Bulk RNA-Seq Reveal Intratumoral Heterogeneity and Tumor Microenvironment Characteristics in Diffuse Large B-Cell Lymphoma
por: Zhao, Yang, et al.
Publicado: (2022)

Corrigendum: Identification of microtube-associated biomarkers in diffuse large B-cell lymphoma and prognosis prediction
por: Wu, Wenqi, et al.
Publicado: (2023)

Whole Transcriptome Data Analysis Reveals Prognostic Signature Genes for Overall Survival Prediction in Diffuse Large B Cell Lymphoma
por: Pan, Mengmeng, et al.
Publicado: (2021)

Multiomics Analysis Reveals the Prognostic Non-tumor Cell Landscape in Glioblastoma Niches
por: Xiao, Zixuan, et al.
Publicado: (2021)

Identification of a 14-Gene Prognostic Signature for Diffuse Large B Cell Lymphoma (DLBCL)
por: Feng, Pengcheng, et al.
Publicado: (2021)

Immunophenotypic Landscape and Prognosis-Related mRNA Signature in Diffuse Large B Cell Lymphoma
por: Jiang, Yanan, et al.
Publicado: (2022)

iPoLNG—An unsupervised model for the integrative analysis of single-cell multiomics data
por: Zhang, Wenyu, et al.
Publicado: (2023)

Detecting the Multiomics Signatures of Factor-Specific Inflammatory Effects on Airway Smooth Muscles
por: Zhang, Yu-Hang, et al.
Publicado: (2021)

Multiomic analysis revealed the regulatory role of the KRT14 gene in eggshell quality
por: Wu, Yan, et al.
Publicado: (2022)

Integrative analysis of a necroptosis-related gene signature of clinical value and heterogeneity in diffuse large B cell lymphoma
por: Pan, Yu-Biao, et al.
Publicado: (2022)

Visual Genomics Analysis Studio as a Tool to Analyze Multiomic Data
por: Hertzman, Rebecca J., et al.
Publicado: (2021)

Comprehensive multiomics analysis of cuproptosis-related gene characteristics in hepatocellular carcinoma
por: Fu, Jie, et al.
Publicado: (2022)

Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma
por: Jin, Zhipeng, et al.
Publicado: (2022)

Hypoxia-related tumor environment correlated with immune infiltration and therapeutic sensitivity in diffuse large B-cell lymphoma
por: Liu, Chen, et al.
Publicado: (2022)

Whole-Genome/Exome Sequencing Uncovers Mutations and Copy Number Variations in Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
por: Zhu, Qiong, et al.
Publicado: (2022)

Overexpression of Rhodopsin or Its Mutants Leads to Energy Metabolism Dysfunction in 661w Cells
por: Liu, Yang, et al.
Publicado: (2022)

Deep Learning in Head and Neck Tumor Multiomics Diagnosis and Analysis: Review of the Literature
por: Wang, Xi, et al.
Publicado: (2021)

Diffuse large B-cell lymphoma with continuously elevated immunoglobulin M following treatment: a case report with pathologic, immunophenotypic, and molecular analyses
por: Xiao, Fei, et al.
Publicado: (2023)

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes
por: Waters, Aoife M, et al.
Publicado: (2015)

TOP2A and CENPF are synergistic master regulators activated in cervical cancer
por: Yu, Beiwei, et al.
Publicado: (2020)

The rs78378222 prevalence and the copy loss of the protective allele A in the tumor tissue of diffuse large B-cell lymphoma
por: Voropaeva, Elena N., et al.
Publicado: (2020)

Novel Loss of Function Variants in CENPF Including a Large Intragenic Deletion in Patients with Strømme Syndrome
por: Misceo, Doriana, et al.
Publicado: (2023)

Construction of a Comprehensive Multiomics Map of Hepatocellular Carcinoma and Screening of Possible Driver Genes
por: Liu, Ziyu, et al.
Publicado: (2020)

Multiomics Analysis Reveals Molecular Abnormalities in Granulosa Cells of Women With Polycystic Ovary Syndrome
por: Zhao, Rusong, et al.
Publicado: (2021)

Editorial: Enhanced biological mechanism study, drug discovery and individualized medicine with single-cell multiomics data and integrative analysis
por: Zhang, Xinying, et al.
Publicado: (2023)

Agent Repurposing for the Treatment of Advanced Stage Diffuse Large B-Cell Lymphoma Based on Gene Expression and Network Perturbation Analysis
por: Xiang, Chenxi, et al.
Publicado: (2021)

A Novel Defined Super-Enhancer Associated Gene Signature to Predict Prognosis in Patients With Diffuse Large B-Cell Lymphoma
por: Xu, Hong, et al.
Publicado: (2022)

Application of apoptosis-related genes in a multiomics-related prognostic model study of gastric cancer
por: Xu, Chengfei, et al.
Publicado: (2022)

Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing
por: Gao, Fan, et al.
Publicado: (2021)

Gene set-based identification of two immune subtypes of diffuse large B cell lymphoma for guiding immune checkpoint blocking therapy
por: Li, Zhe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mc2a3ht571in1e3mrksl0at2ja