HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling

Bone remodeling is a continuous process between bone-forming osteoblasts and bone-resorbing osteoclasts, with any imbalance resulting in metabolic bone disease, including osteopenia. The HERC1 gene encodes an E3 ubiquitin ligase that affects cellular processes by regulating the ubiquitination of tar...

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Detalles Bibliográficos
Autores principales: Pedrazza, Leonardo, Martinez-Martinez, Arturo, Sánchez-de-Diego, Cristina, Valer, José Antonio, Pimenta-Lopes, Carolina, Sala-Gaston, Joan, Szpak, Michal, Tyler-Smith, Chris, Ventura, Francesc, Rosa, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837143/
https://www.ncbi.nlm.nih.gov/pubmed/36635269
http://dx.doi.org/10.1038/s41419-023-05549-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837143/
https://www.ncbi.nlm.nih.gov/pubmed/36635269
http://dx.doi.org/10.1038/s41419-023-05549-x

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