CircRNA MBOAT2 promotes intrahepatic cholangiocarcinoma progression and lipid metabolism reprogramming by stabilizing PTBP1 to facilitate FASN mRNA cytoplasmic export

The carcinogenic role of FASN by regulating lipid metabolism reprogramming has been well-established in multiple tumors. However, whether mechanisms during intrahepatic cholangiocarcinoma (ICC) progression, such as circRNAs, regulate FASN expression remains unknown. Here we demonstrate a lipid metab...

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Detalles Bibliográficos
Autores principales: Yu, Xiaopeng, Tong, Huanjun, Chen, Jialu, Tang, Chenwei, Wang, Shuqing, Si, Yu, Wang, Shouhua, Tang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837196/
https://www.ncbi.nlm.nih.gov/pubmed/36635270
http://dx.doi.org/10.1038/s41419-022-05540-y

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