Renal impairment and abnormal liver function tests in pre-therapeutic phenotype-based DPD deficiency screening using uracilemia: a comprehensive population-based study in 1138 patients

BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) deficiency screening is a pre-therapeutic standard to prevent severe fluoropyrimidine-related toxicity. Although several screening methods exist, the accuracy of their results remains debatable. In France, the uracilemia measurement is considered the...

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Detalles Bibliográficos
Autores principales: Callon, Sidonie, Brugel, Mathias, Botsen, Damien, Royer, Bernard, Slimano, Florian, Feliu, Catherine, Gozalo, Claire, Konecki, Céline, Devie, Bruno, Carlier, Claire, Daire, Viktor, Laurés, Nicolas, Perrier, Marine, Djerada, Zoubir, Bouché, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837271/
https://www.ncbi.nlm.nih.gov/pubmed/36643657
http://dx.doi.org/10.1177/17588359221148536

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