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Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions

OBJECTIVE: The effectiveness of autologous osteoperiosteal transplantation (AOPT) for the treatment of large cystic talar osteochondral lesions (OCLs) should be further evaluated, and the postoperative cartilage coverage is questionable. The purpose of this retrospective observational study was to i...

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Autores principales: Guo, Hao, Chen, Zhuhong, Wei, Yuxuan, Chen, Botao, Sun, Nian, Liu, Yijun, Zeng, Canjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837294/
https://www.ncbi.nlm.nih.gov/pubmed/36380533
http://dx.doi.org/10.1111/os.13586
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author Guo, Hao
Chen, Zhuhong
Wei, Yuxuan
Chen, Botao
Sun, Nian
Liu, Yijun
Zeng, Canjun
author_facet Guo, Hao
Chen, Zhuhong
Wei, Yuxuan
Chen, Botao
Sun, Nian
Liu, Yijun
Zeng, Canjun
author_sort Guo, Hao
collection PubMed
description OBJECTIVE: The effectiveness of autologous osteoperiosteal transplantation (AOPT) for the treatment of large cystic talar osteochondral lesions (OCLs) should be further evaluated, and the postoperative cartilage coverage is questionable. The purpose of this retrospective observational study was to investigate the clinical outcomes of AOPT for the treatment of large cystic talar OCLs and to report second‐look arthroscopic results. METHODS: From June 1, 2017, to June 1, 2021, all talar OCLs at our center were reviewed. Painful cystic lesions treated with AOPT were included in the study. The American Orthopaedic Foot and Ankle Society (AOFAS; 0–100 points) ankle‐hindfoot score, Foot Function Index (FFI; 0–100 points), visual analog scale (VAS; 0–10 points) score, and Tegner score (0–10 points) were used to describe pain and functional outcomes. Furthermore, complications, patient‐reported satisfaction degrees, imaging results (including computed tomography and magnetic resonance), and second‐look arthroscopic evaluation data were also collected for analysis. RESULTS: A total of 29 cases were eligible for the study, and 26 responded to the latest follow‐up request, with a mean follow‐up duration of 30.2 (range, 12–57) months. The AOFAS score improved from 69.2 ± 10.9 preoperatively to 80.9 ± 10.0 at the latest follow‐up (p = 0.000). The FFI score improved from 30.4 ± 18.4 preoperatively to 16.3 ± 14.0 at the latest follow‐up (p = 0.000). The VAS pain score improved from 4.0 ± 2.1 preoperatively to 2.5 ± 2.0 at the latest follow‐up (p = 0.001). No donor site morbidity was found. The mean postoperative MOCART score was 57.7 ± 9.5. Second‐look arthroscopy showed a fibrillated cartilage‐like surface at the lesion site in most cases, while two cases exhibited a nearly normal surface. CONCLUSION: The transplantation of osteoperiosteal cylinder autografts taken from the iliac crest for the treatment of large cystic talar OCLs yielded acceptable clinical results. Good integration of the bony part was observed, but cartilage regeneration remained uncertain.
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spelling pubmed-98372942023-01-18 Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions Guo, Hao Chen, Zhuhong Wei, Yuxuan Chen, Botao Sun, Nian Liu, Yijun Zeng, Canjun Orthop Surg Clinical Articles OBJECTIVE: The effectiveness of autologous osteoperiosteal transplantation (AOPT) for the treatment of large cystic talar osteochondral lesions (OCLs) should be further evaluated, and the postoperative cartilage coverage is questionable. The purpose of this retrospective observational study was to investigate the clinical outcomes of AOPT for the treatment of large cystic talar OCLs and to report second‐look arthroscopic results. METHODS: From June 1, 2017, to June 1, 2021, all talar OCLs at our center were reviewed. Painful cystic lesions treated with AOPT were included in the study. The American Orthopaedic Foot and Ankle Society (AOFAS; 0–100 points) ankle‐hindfoot score, Foot Function Index (FFI; 0–100 points), visual analog scale (VAS; 0–10 points) score, and Tegner score (0–10 points) were used to describe pain and functional outcomes. Furthermore, complications, patient‐reported satisfaction degrees, imaging results (including computed tomography and magnetic resonance), and second‐look arthroscopic evaluation data were also collected for analysis. RESULTS: A total of 29 cases were eligible for the study, and 26 responded to the latest follow‐up request, with a mean follow‐up duration of 30.2 (range, 12–57) months. The AOFAS score improved from 69.2 ± 10.9 preoperatively to 80.9 ± 10.0 at the latest follow‐up (p = 0.000). The FFI score improved from 30.4 ± 18.4 preoperatively to 16.3 ± 14.0 at the latest follow‐up (p = 0.000). The VAS pain score improved from 4.0 ± 2.1 preoperatively to 2.5 ± 2.0 at the latest follow‐up (p = 0.001). No donor site morbidity was found. The mean postoperative MOCART score was 57.7 ± 9.5. Second‐look arthroscopy showed a fibrillated cartilage‐like surface at the lesion site in most cases, while two cases exhibited a nearly normal surface. CONCLUSION: The transplantation of osteoperiosteal cylinder autografts taken from the iliac crest for the treatment of large cystic talar OCLs yielded acceptable clinical results. Good integration of the bony part was observed, but cartilage regeneration remained uncertain. John Wiley & Sons Australia, Ltd 2022-11-15 /pmc/articles/PMC9837294/ /pubmed/36380533 http://dx.doi.org/10.1111/os.13586 Text en © 2022 The Authors. Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Articles
Guo, Hao
Chen, Zhuhong
Wei, Yuxuan
Chen, Botao
Sun, Nian
Liu, Yijun
Zeng, Canjun
Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions
title Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions
title_full Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions
title_fullStr Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions
title_full_unstemmed Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions
title_short Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions
title_sort autologous osteoperiosteal transplantation for the treatment of large cystic talar osteochondral lesions
topic Clinical Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837294/
https://www.ncbi.nlm.nih.gov/pubmed/36380533
http://dx.doi.org/10.1111/os.13586
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