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Development of fluorescence-labeled antibody for immune checkpoint inhibitor using engineered probiotics

Here, we developed a genetically modified lactic acid bacteria (gmLAB) that produces green fluorescent protein (GFP)-conjugating, anti-programmed death-ligand 1 (PD-L1) single-chain variable fragments (scFv) for use as an anti-cancer device that targets immune checkpoint molecules. Since PD-L1 plays...

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Detalles Bibliográficos
Autores principales:	Namai, Fu, Sumiya, Shunsuke, Nomura, Natsumi, Sato, Takashi, Shimosato, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837357/ https://www.ncbi.nlm.nih.gov/pubmed/36635518 http://dx.doi.org/10.1186/s13568-023-01509-y

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