Caveolin‐1 inhibition mediates the opposing effects of alcohol on γ‐secretase activity in arterial endothelial and smooth muscle cells

Notch is important to vessel homeostasis. We investigated the mechanistic role of caveolin‐1 (Cav‐1) in mediating the effects of alcohol (Ethanol/EtOH) on the γ‐secretase proteolytic activity necessary for Notch signaling in vascular cells. Human coronary artery endothelial cells (HCAEC) were treate...

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Detalles Bibliográficos
Autores principales: Rajendran, Naresh K., Liu, Weimin, Cahill, Paul A., Redmond, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837422/
https://www.ncbi.nlm.nih.gov/pubmed/36635975
http://dx.doi.org/10.14814/phy2.15544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837422/
https://www.ncbi.nlm.nih.gov/pubmed/36635975
http://dx.doi.org/10.14814/phy2.15544

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