Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas

Adult T-cell leukemia/lymphoma (ATLL) is one of the aggressive peripheral T-cell neoplasms with a poor prognosis. Accumulating evidence demonstrates that escape from adaptive immunity is a hallmark of ATLL pathogenesis. However, the mechanisms by which ATLL cells evade natural killer (NK)-cell–media...

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Detalles Bibliográficos
Autores principales: Chiba, Masahiro, Shimono, Joji, Ishio, Takashi, Takei, Norio, Kasahara, Kohei, Ogasawara, Reiki, Ara, Takahide, Goto, Hideki, Izumiyama, Koh, Otsuguro, Satoko, Perera, Liyanage P., Hasegawa, Hiroo, Maeda, Michiyuki, Hashino, Satoshi, Maenaka, Katsumi, Teshima, Takanori, Waldmann, Thomas A., Yang, Yibin, Nakagawa, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837448/
https://www.ncbi.nlm.nih.gov/pubmed/35921533
http://dx.doi.org/10.1182/blood.2022015646

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