Gene expression analysis of antioxidant and DNA methylation on the rat liver after 4-week wood preservative chromated copper arsenate exposure

Our previous 4-week repeated dose toxicity study showed that wood preservative chromated copper arsenate (CCA) induced hepatocellular hypertrophy accompanied by biochemical hepatic dysfunction and an increase in oxidative stress marker, 8-hydroxydeoxyguanosine, in female rats. To further explore the...

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Detalles Bibliográficos
Autores principales: Takahashi, Naofumi, Yamaguchi, Satoru, Ohtsuka, Ryouichi, Takeda, Makio, Yoshida, Toshinori, Kosaka, Tadashi, Harada, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837468/
https://www.ncbi.nlm.nih.gov/pubmed/36683727
http://dx.doi.org/10.1293/tox.2022-0093

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