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Inhibition of ANGPT2 activates autophagy during hypertrophic scar formation via PI3K/AKT/mTOR pathway()

BACKGROUND: Hypertrophic scar (HS), a fibroproliferative disorder caused by aberrant wound healing following skin injuries such as burns, lacerations and surgery, is characterized by invasive proliferation of fibroblasts and excessive extracellular matrix (ECM) accumulation. The dysregulation of aut...

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Detalles Bibliográficos
Autores principales: Chen, Hongxin, Xu, Kai, Sun, Chao, Gui, Si, Wu, Juanjuan, Wang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837657/
https://www.ncbi.nlm.nih.gov/pubmed/36272879
http://dx.doi.org/10.1016/j.abd.2021.12.005

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