Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease

 Converging lines of evidence suggest that aerobic exercise impacts Parkinson’s disease (PD) motor symptoms and might slow it’s progression. We provide an overview of the ongoing randomized clinical trials (RCTs) on aerobic exercise in PD. We found six RCTs with sample sizes between 28 and 370 and a...

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Autores principales: Schootemeijer, Sabine, Darweesh, Sirwan K.L., de Vries, Nienke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837678/
https://www.ncbi.nlm.nih.gov/pubmed/36336942
http://dx.doi.org/10.3233/JPD-229006
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author Schootemeijer, Sabine
Darweesh, Sirwan K.L.
de Vries, Nienke M.
author_facet Schootemeijer, Sabine
Darweesh, Sirwan K.L.
de Vries, Nienke M.
author_sort Schootemeijer, Sabine
collection PubMed
description  Converging lines of evidence suggest that aerobic exercise impacts Parkinson’s disease (PD) motor symptoms and might slow it’s progression. We provide an overview of the ongoing randomized clinical trials (RCTs) on aerobic exercise in PD. We found six RCTs with sample sizes between 28 and 370 and a follow-up between 8 weeks and 18 months. PD motor symptoms is mostly used as primary outcome while various secondary outcomes are reported. We need more trials that use both clinical endpoints and markers of neuroplasticity, and provide insight into the optimal exercise mode, duration and intensity.
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spelling pubmed-98376782023-01-30 Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease Schootemeijer, Sabine Darweesh, Sirwan K.L. de Vries, Nienke M. J Parkinsons Dis Research Report  Converging lines of evidence suggest that aerobic exercise impacts Parkinson’s disease (PD) motor symptoms and might slow it’s progression. We provide an overview of the ongoing randomized clinical trials (RCTs) on aerobic exercise in PD. We found six RCTs with sample sizes between 28 and 370 and a follow-up between 8 weeks and 18 months. PD motor symptoms is mostly used as primary outcome while various secondary outcomes are reported. We need more trials that use both clinical endpoints and markers of neuroplasticity, and provide insight into the optimal exercise mode, duration and intensity. IOS Press 2022-12-16 /pmc/articles/PMC9837678/ /pubmed/36336942 http://dx.doi.org/10.3233/JPD-229006 Text en © 2022 – The authors. Published by IOS Press https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Report
Schootemeijer, Sabine
Darweesh, Sirwan K.L.
de Vries, Nienke M.
Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
title Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
title_full Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
title_fullStr Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
title_full_unstemmed Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
title_short Clinical Trial Highlights – Aerobic Exercise for Parkinson’s Disease
title_sort clinical trial highlights – aerobic exercise for parkinson’s disease
topic Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837678/
https://www.ncbi.nlm.nih.gov/pubmed/36336942
http://dx.doi.org/10.3233/JPD-229006
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