Nigral Iron Deposition Influences Disease Severity by Modulating the Effect of Parkinson’s Disease on Brain Networks

BACKGROUND: In Parkinson’s disease (PD), excessive iron deposition in the substantia nigra may exacerbate α-synuclein aggregation, facilitating the degeneration of dopaminergic neurons and their neural projection. OBJECTIVE: To investigate the interaction effect between nigral iron deposition and PD...

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Detalles Bibliográficos
Autores principales: Wen, Jiaqi, Guo, Tao, Wu, Jingjing, Bai, Xueqin, Zhou, Cheng, Wu, Haoting, Liu, Xiaocao, Chen, Jingwen, Cao, Zhengye, Gu, Luyan, Pu, Jiali, Zhang, Baorong, Zhang, Minming, Guan, Xiaojun, Xu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837680/
https://www.ncbi.nlm.nih.gov/pubmed/36336939
http://dx.doi.org/10.3233/JPD-223372

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