Brain Alterations in Aged OVT73 Sheep Model of Huntington’s Disease: An MRI Based Approach

BACKGROUND: Huntington’s disease (HD) is a fatal neurodegenerative autosomal dominant disorder with prevalence of 1 : 20000 that has no effective treatment to date. Translatability of candidate therapeutics could be enhanced by additional testing in large animal models because of similarities in bra...

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Detalles Bibliográficos
Autores principales: Taghian, Toloo, Gallagher, Jillian, Batcho, Erin, Pullan, Caitlin, Kuchel, Tim, Denney, Thomas, Perumal, Raj, Moore, Shamika, Muirhead, Robb, Herde, Paul, Johns, Daniel, Christou, Chris, Taylor, Amanda, Passler, Thomas, Pulaparthi, Sanjana, Hall, Erin, Chandra, Sundeep, O’Neill, Charles A., Gray-Edwards, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837686/
https://www.ncbi.nlm.nih.gov/pubmed/36189602
http://dx.doi.org/10.3233/JHD-220526

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