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Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach

AIM: To test the agreement between a newly developed micro-magnetic resonance imaging (MRI) analysis of the subchondral bone and the micro-computed tomography (CT) approach. METHODS: Samples obtained from 10 patients with osteoarthritis undergoing total hip arthroplasty were scanned with a 7.0 T mic...

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Autores principales: Duvančić, Tea, Škokić, Siniša, Erjavec, Igor, Plečko, Mihovil, Bohaček, Ivan, Gajović, Srećko, Delimar, Domagoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837720/
https://www.ncbi.nlm.nih.gov/pubmed/36597563
http://dx.doi.org/10.3325/cmj.2022.63.515
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author Duvančić, Tea
Škokić, Siniša
Erjavec, Igor
Plečko, Mihovil
Bohaček, Ivan
Gajović, Srećko
Delimar, Domagoj
author_facet Duvančić, Tea
Škokić, Siniša
Erjavec, Igor
Plečko, Mihovil
Bohaček, Ivan
Gajović, Srećko
Delimar, Domagoj
author_sort Duvančić, Tea
collection PubMed
description AIM: To test the agreement between a newly developed micro-magnetic resonance imaging (MRI) analysis of the subchondral bone and the micro-computed tomography (CT) approach. METHODS: Samples obtained from 10 patients with osteoarthritis undergoing total hip arthroplasty were scanned with a 7.0 T micro-MRI. Proton density-weighted images and proton density-weighted images with fat suppression were obtained. The results were validated with a micro-CT device. Micro-MRI and micro-CT scans of the same sample were aligned, and regions of interest were delineated on equal areas of the sample. Bone volume fraction was calculated by using in-house plugins. The agreement between the methods was tested with Bland-Altman analysis. RESULTS: The agreement between the methods was good, with average difference of 2.167%. The differences between the methods were not significant (P = 0.272, t test). CONCLUSION: The novel micro-MRI approach could be used for subchondral bone analysis. With further optimization for clinical MRI machines, the approach can be also used in the diagnostics of hip osteoarthritis.
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spelling pubmed-98377202023-01-24 Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach Duvančić, Tea Škokić, Siniša Erjavec, Igor Plečko, Mihovil Bohaček, Ivan Gajović, Srećko Delimar, Domagoj Croat Med J Research Article AIM: To test the agreement between a newly developed micro-magnetic resonance imaging (MRI) analysis of the subchondral bone and the micro-computed tomography (CT) approach. METHODS: Samples obtained from 10 patients with osteoarthritis undergoing total hip arthroplasty were scanned with a 7.0 T micro-MRI. Proton density-weighted images and proton density-weighted images with fat suppression were obtained. The results were validated with a micro-CT device. Micro-MRI and micro-CT scans of the same sample were aligned, and regions of interest were delineated on equal areas of the sample. Bone volume fraction was calculated by using in-house plugins. The agreement between the methods was tested with Bland-Altman analysis. RESULTS: The agreement between the methods was good, with average difference of 2.167%. The differences between the methods were not significant (P = 0.272, t test). CONCLUSION: The novel micro-MRI approach could be used for subchondral bone analysis. With further optimization for clinical MRI machines, the approach can be also used in the diagnostics of hip osteoarthritis. Croatian Medical Schools 2022-12 /pmc/articles/PMC9837720/ /pubmed/36597563 http://dx.doi.org/10.3325/cmj.2022.63.515 Text en Copyright © 2022 by the Croatian Medical Journal. All rights reserved. https://creativecommons.org/licenses/by/2.5/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Duvančić, Tea
Škokić, Siniša
Erjavec, Igor
Plečko, Mihovil
Bohaček, Ivan
Gajović, Srećko
Delimar, Domagoj
Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
title Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
title_full Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
title_fullStr Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
title_full_unstemmed Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
title_short Novel micro-MRI approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-CT approach
title_sort novel micro-mri approach for subchondral trabecular bone analysis in patients with hip osteoarthritis is comparable to micro-ct approach
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837720/
https://www.ncbi.nlm.nih.gov/pubmed/36597563
http://dx.doi.org/10.3325/cmj.2022.63.515
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