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Nicotinamide Mononucleotide Prevents Cisplatin-Induced Mitochondrial Defects in Cortical Neurons Derived from Human Induced Pluripotent Stem Cells

BACKGROUND: Chemotherapy-induced cognitive impairment (CICI) is a neurotoxic side effect of chemotherapy that has yet to have an effective treatment. OBJECTIVE: Using cisplatin, a platinum-based chemotherapy together with excitatory cortical neurons derived from human induced pluripotent cells (iPSC...

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Detalles Bibliográficos
Autores principales:	Rashid, Mohammad Abdur, Oliveros, Alfredo, Kim, Yu Shin, Jang, Mi-Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837732/ https://www.ncbi.nlm.nih.gov/pubmed/36721392 http://dx.doi.org/10.3233/BPL-220143

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