Enantioselective Single and Dual α-C–H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer

[Image: see text] Cyclic amines are ubiquitous structural motifs found in pharmaceuticals and biologically active natural products, making methods for their elaboration via direct C–H functionalization of considerable synthetic value. Herein, we report the development of an iron-based biocatalytic s...

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Detalles Bibliográficos
Autores principales: Ren, Xinkun, Couture, Bo M., Liu, Ningyu, Lall, Manjinder S., Kohrt, Jeffrey T., Fasan, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837850/
https://www.ncbi.nlm.nih.gov/pubmed/36542059
http://dx.doi.org/10.1021/jacs.2c10775

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