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MTX-PEG-modified CG/DMMA polymeric micelles for targeted delivery of doxorubicin to induce synergistic autophagic death against triple-negative breast cancer

The chemotherapy of triple-negative breast cancer based on doxorubicin (DOX) regimens suffers from great challenges on toxicity and autophagy raised off-target. In this study, a conjugate methotrexate-polyethylene glycol (shorten as MTX-PEG)-modified CG/DMMA polymeric micelles were prepared to endue...

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Detalles Bibliográficos
Autores principales:	Cao, Zhiwen, Liu, Rui, Li, Yang, Luo, Xinyi, Hua, Zhenglai, Wang, Xiangpeng, Xue, Zeyu, Zhang, Zhengjia, Lu, Cheng, Lu, Aiping, Liu, Yuanyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837947/ https://www.ncbi.nlm.nih.gov/pubmed/36635685 http://dx.doi.org/10.1186/s13058-022-01599-9

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