Cargando…

Proximal tubule-derived exosomes contribute to mesangial cell injury in diabetic nephropathy via miR-92a-1-5p transfer

BACKGROUND: Diabetic nephropathy (DN) is an increasing threat to human health and regarded to be the leading cause of end-stage renal disease worldwide. Exosomes delivery may play a key role in cross-talk among kidney cells and the progression of DN. However, the mechanisms underlying exosomes in DN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Yi-Chun, Kuo, Mei-Chuan, Hung, Wei-Wen, Wu, Ping-Hsun, Chang, Wei-An, Wu, Ling-Yu, Lee, Su-Chu, Hsu, Ya-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838003/ https://www.ncbi.nlm.nih.gov/pubmed/36639674 http://dx.doi.org/10.1186/s12964-022-00997-y

Ejemplares similares

Autocrine Exosomal Fibulin-1 as a Target of MiR-1269b Induces Epithelial–Mesenchymal Transition in Proximal Tubule in Diabetic Nephropathy
por: Tsai, Yi-Chun, et al.
Publicado: (2021)

Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy
por: Tsai, Yi-Chun, et al.
Publicado: (2018)

The Interaction of miR-378i-Skp2 Regulates Cell Senescence in Diabetic Nephropathy
por: Tsai, Yi-Chun, et al.
Publicado: (2018)

Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity
por: Jella, Kishore Kumar, et al.
Publicado: (2016)

Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Proximal Tubular Epithelial Cells through miR-545-3p–TNFSF10
por: Kuo, Mei-Chuan, et al.
Publicado: (2021)

KITLG Promotes Glomerular Endothelial Cell Injury in Diabetic Nephropathy by an Autocrine Effect
por: Huang, Jiun-Chi, et al.
Publicado: (2022)

Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation
por: Thomas, Haryana Y., et al.
Publicado: (2022)

Evaluation of the efficacy of Abelmoschus manihot (L.) on diabetic nephropathy by analyzing biomarkers in the glomeruli and proximal and distal convoluted tubules of the kidneys
por: Yu, Hongmei, et al.
Publicado: (2023)

Warfarin-Related Nephropathy Manifested as Diffuse Mesangial Proliferative Glomerulonephritis
por: Acquah, Frederick, et al.
Publicado: (2022)

Mesangial Cell–Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2
por: Yu, Mengjie, et al.
Publicado: (2022)

Role of Calbindin-D28k in Diabetes-Associated Advanced Glycation End-Products-Induced Renal Proximal Tubule Cell Injury
por: Huang, Kuo-How, et al.
Publicado: (2019)

The Proximal Tubule Cell in Experimental Hydronephrosis
por: Novikoff, Alex B.
Publicado: (1959)

Rheogenic transport in the renal proximal tubule
Publicado: (1983)

Is the proximal tubule the focus of tubulointerstitial fibrosis?
por: Peng, Zhi, et al.
Publicado: (2023)

VPS34 functions in the proximal tubule
por: Allison, Susan J.
Publicado: (2023)

New Insights into the Pathogenesis of Diabetic Nephropathy: Proximal Renal Tubules Are Primary Target of Oxidative Stress in Diabetic Kidney
por: Haraguchi, Ryuma, et al.
Publicado: (2020)

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip
por: Sakolish, Courtney, et al.
Publicado: (2018)

Ultrastructural identification of developing proximal tubules based on three‐dimensional reconstruction
por: Cong, Jing, et al.
Publicado: (2021)

Autophagy in proximal tubules protects against acute kidney injury
por: Jiang, Man, et al.
Publicado: (2012)

Liuwei Dihuang Pills Inhibit Podocyte Injury and Alleviate IgA Nephropathy by Directly Altering Mesangial Cell-Derived Exosome Function and Secretion
por: Zhu, Xiaodong, et al.
Publicado: (2022)

Insertion of an axial electrode into renal proximal tubule.
por: Spring, K. R.
Publicado: (1972)

Conductive properties of the proximal tubule in Necturus kidney
Publicado: (1980)

Analysis of standing droplets in rat proximal tubules
Publicado: (1982)

Kinetics of Na(+) transport in necturus proximal tubule
por: Spring, KR, et al.
Publicado: (1977)

Isosmotic volume reabsorption in rat proximal tubule
Publicado: (1980)

Iron Is Filtered by the Kidney and Is Reabsorbed by the Proximal Tubule
por: Wareing, Mark, et al.
Publicado: (2021)

Proximal Tubule Dysfunction Secondary to Salicylate Intoxication
por: Taylor, Zachary C., et al.
Publicado: (2022)

The Proximal Tubule Toxicity of Immunoglobulin Light Chains
por: Sirac, Christophe, et al.
Publicado: (2021)

Renal proximal tubule cells: power and finesse
por: Fuchs, Michaela A.A., et al.
Publicado: (2023)

A multicenter, prospective, observational study to determine association of mesangial C1q deposition with renal outcomes in IgA nephropathy
por: Tan, Li, et al.
Publicado: (2021)

PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation
por: Gu, Xiaorong, et al.
Publicado: (2021)

A Micropuncture Study of HCO(3) Reabsorption by the Hypertrophied Proximal Tubule
por: Bank, Norman, et al.
Publicado: (1978)

Changes in the gene expression programs of renal mesangial cells during diabetic nephropathy
por: Brunskill, Eric W, et al.
Publicado: (2012)

Vorapaxar treatment reduces mesangial expansion in streptozotocin-induced diabetic nephropathy in mice
por: Waasdorp, Maaike, et al.
Publicado: (2018)

NAD(+) Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy
por: Li, Xue, et al.
Publicado: (2022)

Clinicopathologic and Prognostic Study of Primary IgA Nephropathy With Light Chain λ Restriction in the Mesangial Deposits
por: Zhang, Ji, et al.
Publicado: (2022)

Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors
por: Kogot-Levin, Aviram, et al.
Publicado: (2020)

Light Chain Restriction in Proximal Tubules—Implications for Light Chain Proximal Tubulopathy
por: Büttner-Herold, Maike, et al.
Publicado: (2022)

POTASSIUM ACCUMULATION IN THE PROXIMAL CONVOLUTED TUBULES OF THE FROG'S KIDNEY
por: Conway, E. J., et al.
Publicado: (1946)

Osmotic Volume Flow in the Proximal Tubule of Necturus Kidney
por: Bentzel, Carl J., et al.
Publicado: (1968)

Cannot write session to /tmp/vufind_sessions/sess_ckcjnq0r518e07oi86d1jm1njh