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Aldosterone inhibits Dot1l expression in guinea pig cochlea

BACKGROUND: Aldosterone relieves transcriptional repression of epithelial sodium channel (ENaC) by inhibiting Dot1a and Af9 expression and their interaction with ENaC promoter in various tissues. Expressions of ENaC and Af9 in inner ear have been identified. However, it is not known how Dot1l is reg...

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Detalles Bibliográficos
Autores principales:	Zhong, Shixun, Zhang, Biyun, Qin, Li, Wang, Qianying, Luo, Xiaoli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838020/ https://www.ncbi.nlm.nih.gov/pubmed/36639782 http://dx.doi.org/10.1186/s40001-023-00994-y

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