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SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved to variants associated with milder disease. We employed the k18-hACE2 mouse model to study how differences in the course of infection by SARS-CoV-2 variants alpha, delta, and omicron relate to tissue pathology and the immune re...
Autores principales: | Gonçalves, Rute, Couto, Joana, Ferreirinha, Pedro, Costa, José Maria, Silvério, Diogo, Silva, Marta L., Fernandes, Ana Isabel, Madureira, Pedro, Alves, Nuno L., Lamas, Sofia, Saraiva, Margarida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838028/ https://www.ncbi.nlm.nih.gov/pubmed/36687317 http://dx.doi.org/10.1016/j.isci.2023.105972 |
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