Long noncoding RNAs: glycolysis regulators in gynaecologic cancers

The three most common gynaecologic cancers that seriously threaten female lives and health are ovarian cancer, cervical cancer, and endometrial cancer. Glycolysis plays a vital role in gynaecologic cancers. Several long noncoding RNAs (lncRNAs) are known to function as oncogenic molecules. LncRNAs i...

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Detalles Bibliográficos
Autores principales: Lv, Nengyuan, Shen, Siyi, Chen, Qianying, Tong, Jinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838043/
https://www.ncbi.nlm.nih.gov/pubmed/36639695
http://dx.doi.org/10.1186/s12935-023-02849-2
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author Lv, Nengyuan
Shen, Siyi
Chen, Qianying
Tong, Jinyi
author_facet Lv, Nengyuan
Shen, Siyi
Chen, Qianying
Tong, Jinyi
author_sort Lv, Nengyuan
collection PubMed
description The three most common gynaecologic cancers that seriously threaten female lives and health are ovarian cancer, cervical cancer, and endometrial cancer. Glycolysis plays a vital role in gynaecologic cancers. Several long noncoding RNAs (lncRNAs) are known to function as oncogenic molecules. LncRNAs impact downstream target genes by acting as ceRNAs, guides, scaffolds, decoys, or signalling molecules. However, the role of glycolysis-related lncRNAs in regulating gynaecologic cancers remains poorly understood. In this review, we emphasize the functional roles of many lncRNAs that have been found to promote glycolysis in gynaecologic cancers and discuss reasonable strategies for future research.
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spelling pubmed-98380432023-01-14 Long noncoding RNAs: glycolysis regulators in gynaecologic cancers Lv, Nengyuan Shen, Siyi Chen, Qianying Tong, Jinyi Cancer Cell Int Review The three most common gynaecologic cancers that seriously threaten female lives and health are ovarian cancer, cervical cancer, and endometrial cancer. Glycolysis plays a vital role in gynaecologic cancers. Several long noncoding RNAs (lncRNAs) are known to function as oncogenic molecules. LncRNAs impact downstream target genes by acting as ceRNAs, guides, scaffolds, decoys, or signalling molecules. However, the role of glycolysis-related lncRNAs in regulating gynaecologic cancers remains poorly understood. In this review, we emphasize the functional roles of many lncRNAs that have been found to promote glycolysis in gynaecologic cancers and discuss reasonable strategies for future research. BioMed Central 2023-01-13 /pmc/articles/PMC9838043/ /pubmed/36639695 http://dx.doi.org/10.1186/s12935-023-02849-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Lv, Nengyuan
Shen, Siyi
Chen, Qianying
Tong, Jinyi
Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
title Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
title_full Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
title_fullStr Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
title_full_unstemmed Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
title_short Long noncoding RNAs: glycolysis regulators in gynaecologic cancers
title_sort long noncoding rnas: glycolysis regulators in gynaecologic cancers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838043/
https://www.ncbi.nlm.nih.gov/pubmed/36639695
http://dx.doi.org/10.1186/s12935-023-02849-2
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AT tongjinyi longnoncodingrnasglycolysisregulatorsingynaecologiccancers

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