A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy

BACKGROUND: Chimeric antigen receptor (CAR) T cells and immune checkpoint blockades (ICBs) have made remarkable breakthroughs in cancer treatment, but the efficacy is still limited for solid tumors due to tumor antigen heterogeneity and the tumor immune microenvironment. The restrained treatment eff...

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Detalles Bibliográficos
Autores principales: Zhang, Zongliang, Wang, Guoqing, Zhong, Kunhong, Chen, Yongdong, Yang, Nian, Lu, Qizhong, Yuan, Boyang, Wang, Zeng, Li, Hexian, Guo, Liping, Zhang, Ruyuan, Wu, Zhiguo, Zheng, Meijun, Zhao, Shasha, Tang, Xin, Shao, Bin, Tong, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838049/
https://www.ncbi.nlm.nih.gov/pubmed/36635683
http://dx.doi.org/10.1186/s12967-023-03875-4

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