Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells

AIM: Elevated brain deposits of amyloid beta (Aβ(40)) contribute to neuropathology and cognitive dysfunction in Alzheimer’s disease (AD). However, the role of the blood-brain barrier (BBB) as an interface for the transfer of Aβ(40) from the periphery into the brain is not well characterized. In addi...

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Detalles Bibliográficos
Autores principales: Osborne, Olivia M., Kowalczyk, Jennifer M., Louis, Kelssey D. Pierre, Daftari, Manav T., Colbert, Brett M., Naranjo, Oandy, Torices, Silvia, András, Ibolya E., Dykxhoorn, Derek M., Toborek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838065/
https://www.ncbi.nlm.nih.gov/pubmed/36649440
http://dx.doi.org/10.20517/evcna.2022.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838065/
https://www.ncbi.nlm.nih.gov/pubmed/36649440
http://dx.doi.org/10.20517/evcna.2022.22

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