Cargando…

Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells

AIM: Elevated brain deposits of amyloid beta (Aβ(40)) contribute to neuropathology and cognitive dysfunction in Alzheimer’s disease (AD). However, the role of the blood-brain barrier (BBB) as an interface for the transfer of Aβ(40) from the periphery into the brain is not well characterized. In addi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Osborne, Olivia M., Kowalczyk, Jennifer M., Louis, Kelssey D. Pierre, Daftari, Manav T., Colbert, Brett M., Naranjo, Oandy, Torices, Silvia, András, Ibolya E., Dykxhoorn, Derek M., Toborek, Michal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838065/ https://www.ncbi.nlm.nih.gov/pubmed/36649440 http://dx.doi.org/10.20517/evcna.2022.22

Ejemplares similares

Pericyte infection by HIV-1: a fatal attraction
por: Naranjo, Oandy, et al.
Publicado: (2022)

Anti-amyloid: An antibody to cure Alzheimer’s or an attitude
por: Osborne, Olivia M., et al.
Publicado: (2023)

In Vivo Targeting of the Neurovascular Unit: Challenges and Advancements
por: Naranjo, Oandy, et al.
Publicado: (2021)

Extracellular vesicle-mediated amyloid transfer to neural progenitor cells: implications for RAGE and HIV infection
por: András, Ibolya E., et al.
Publicado: (2020)

HIV-1 and Amyloid Beta Remodel Proteome of Brain Endothelial Extracellular Vesicles
por: András, Ibolya E., et al.
Publicado: (2020)

Extracellular vesicle-Serpine-1 affects neural progenitor cell mitochondrial functions and synaptic density: modulation by amyloid beta and HIV-1
por: András, Ibolya E., et al.
Publicado: (2023)

Extracellular Vesicle-Serpine-1 Affects Neural Progenitor Cell Mitochondrial Networks and Synaptic Density: Modulation by Amyloid Beta and HIV-1
por: András, Ibolya E., et al.
Publicado: (2023)

Occludin regulates HIV-1 infection by modulation of the interferon stimulated OAS gene family
por: Torices, Silvia, et al.
Publicado: (2023)

Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family
por: Torices, Silvia, et al.
Publicado: (2023)

Expression of SARS-CoV-2-related Receptors in Cells of the Neurovascular Unit: Implications for HIV-1 Infection
por: Torices, Silvia, et al.
Publicado: (2021)

Extracellular vesicles of the blood-brain barrier
por: András, Ibolya E, et al.
Publicado: (2015)

Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection
por: Torices, Silvia, et al.
Publicado: (2021)

Occludin: a gatekeeper of brain Infection by HIV-1
por: Torices, Silvia, et al.
Publicado: (2023)

Exercise Modulates Redox-Sensitive Small GTPase Activity in the Brain Microvasculature in a Model of Brain Metastasis Formation
por: Wolff, Gretchen, et al.
Publicado: (2014)

Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders
por: Fattakhov, Nikolai, et al.
Publicado: (2021)

Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art
por: Nourbakhsh, Aida, et al.
Publicado: (2021)

Haematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic endothelium
por: Ghersi, Joey J., et al.
Publicado: (2023)

Usher Syndrome in the Inner Ear: Etiologies and Advances in Gene Therapy
por: de Joya, Evan M., et al.
Publicado: (2021)

Selective Disruption of the Blood–Brain Barrier by Zika Virus
por: Leda, Ana Rachel, et al.
Publicado: (2019)

Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo
por: Dignum, Tessa, et al.
Publicado: (2021)

Occludin, caveolin‐1, and Alix form a multi‐protein complex and regulate HIV‐1 infection of brain pericytes
por: Torices, Silvia, et al.
Publicado: (2020)

Urinary incontinence in women: biofeedback as an innovative treatment method
por: Kopańska, Marta, et al.
Publicado: (2020)

Endothelium-Derived Extracellular Vesicles Associate with Poor Prognosis in Metastatic Colorectal Cancer
por: Nanou, Afroditi, et al.
Publicado: (2020)

Voluntary exercise protects against methamphetamine-induced oxidative stress in brain microvasculature and disruption of the blood–brain barrier
por: Toborek, Michal, et al.
Publicado: (2013)

Circulating galectin-3 promotes tumor-endothelium-adhesion by upregulating ICAM-1 in endothelium-derived extracellular vesicles
por: Wang, Lei, et al.
Publicado: (2022)

Extracellular vesicles: how they interact with endothelium, potentially contributing to metastatic cancer cell implants
por: Bern, Murray M.
Publicado: (2017)

Homing of mRNA-Modified Endothelial Progenitor Cells to Inflamed Endothelium
por: Canjuga, Denis, et al.
Publicado: (2022)

P-bodies and RNAi: The missing link?
por: Dykxhoorn, Derek M
Publicado: (2005)

The Paradox of HIV Blood–Brain Barrier Penetrance and Antiretroviral Drug Delivery Deficiencies
por: Osborne, Olivia, et al.
Publicado: (2020)

Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors
por: Moldenhauer, Anja, et al.
Publicado: (2008)

Hematopoietic stem and progenitor cells take the route through the bone marrow endothelium
por: Kalafati, Lydia, et al.
Publicado: (2020)

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
por: Akbar, Naveed, et al.
Publicado: (2017)

Characterization of Human Transition Zone Reveals a Putative Progenitor-Enriched Niche of Corneal Endothelium
por: Yam, Gary Hin-Fai, et al.
Publicado: (2019)

Rings of membrane sterols surround the openings of vesicles and fenestrae, in capillary endothelium
Publicado: (1983)

Contributing role of extracellular vesicles on vascular endothelium haemostatic balance in cancer
por: Bouvy, Céline, et al.
Publicado: (2014)

Contribution of a GATA4-Expressing Hematopoietic Progenitor Lineage to the Adult Mouse Endothelium
por: Carmona, Rita, et al.
Publicado: (2020)

Evaluation of Strategies Aimed at Improving Liver Progenitor Cell Rolling and Subsequent Adhesion to the Endothelium
por: Dollet, Pierre Edouard, et al.
Publicado: (2020)

Hematopoietic stem and progenitor cells use podosomes to transcellularly cross the bone marrow endothelium
por: Rademakers, Timo, et al.
Publicado: (2020)

The Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation
por: Mikołajczyk, Klaudia, et al.
Publicado: (2021)

Silencing Viral Infection
por: Dykxhoorn, Derek M, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_gtefn3lhvjeacrc71j002j3ms8